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Case 093

History/Physical

History/Physical
Neuroradiology
Neuroradiology Interpretation
Neurosurgery
Neuropathology
Neuropathology Interpretation and Diagnosis

History/Physical:

44-year-old right-handed male.

Progressive headache over the past year.

MRI axial T2

MRI axial DWI

MRI coronal T1

The mass with irregular margins causes obstruction of the right lateral ventricle.

The mass has high signal on diffusion. This suggests hypercellularity.

The mass has solid and cystic components. The inferior margin of the mass blocks the foramen of Monroe, resulting in hydrocephalus.

Tx: Craniotomy and resection of brain tumour.

H&E, 10x

H&E, 40x

Synaptophysin, 40x

Diagnosis: Central neurocytoma

Monotonous population of rounded cells in enfilades and rosette-like arrangements.

Delicate branching capillaries, rounded tumour cell nuclei with perinuclear clearing (imitating oligodendroglioma).

Synaptophysin expression confirms neuronal lineage.

Case 092 Case 094

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